XIAO shuqi
XIAO Shuqi
Ph.D., Professor
Born in Jan.1979, Kaifeng City, Henan, China
Contact
Address: College of Veterinary Medicine, Northwest A&F University
No. 22 Xinong Road, Yangling, 712100, Shaanxi, China.
Email(s): xiaoshuqi@nwsuaf.edu.cn, shqxiaojd@hotmail.com
Mobile: +86 187 0092 8448
Telephone: +86-(0)29-8709-1117
Fax: +86-(0)29-8709-103
1. Education and Work Experience
01.2018 – now, Professor, College of Veterinary Medicine, Northwest A&F University
09.2014 – 08.2015, Visiting Scholar, Virology Division, Department of Pathology, Faculty of Biology, University of Cambridge, U.K.
06.2012 – 12.2017, Associate Professor, College of Veterinary Medicine, Northwest A&F University
07.2010 – 06.2012, Postdoctoral training, School of Life Sciences, Sun Yat-Sen University
09.2007 – 06.2010, Ph.D., Biology (Biotechnology), School of Life Sciences, Sun Yat-Sen University
09.2004 – 07.2007, Master, Animal Genetic, Breeding and Reproduction, College of Animal Science and Veterinary Medicine, Jilin University
09.1998 – 07.2003, Bachelor, Animal Science, College of Animal Science and Veterinary Medicine, Henan Institute of Science and Technology
2. Research and Teaching
Research interests:
Molecular pathogenesis, prevention and control of infectious disease in swine and bovine, such as porcine reproductive and respiratory syndrome, porcine epidemic diarrhea, bovine viral diarrhea.
Teaching:
Veterinary Microbiology, Special Topics in Swine Diseases for bachelor students.
Laboratory Diagnostic Technology for Animal Infectious Diseases for master students.
Veterinary Molecular Virology for doctoral students.
3. Memberships and Academic Services
Committee Member of the Branch of Animal Infectious Diseases, Biotechnology, Veterinary Public Health of the Chinese Association of Animal Science and Veterinary Medicine
Editorial board member of Frontiers in Microbiology
4. Honors and Awards
Shaanxi Youth Science and Technology Award, 2020
Shaanxi Youth Science and Technology Pacesetter, 2020
Shaanxi Science Foundation for Distinguished Young Scholars, 2021
5. Publications
[1] Zifang Zheng, Xiali Fu, Xue Ling, Huanhuan Sun, Yang Li, Zhiqian Ma, Bingjie Wei, Haixue Zheng, Shuqi Xiao*. The host cells actively resist PRRSV infection via the IRF8-miR-10a-SRP14 regulatory pathway. Journal of Virology , 96(7):e0000322 (2022).
[2] Yingtong Feng, Xuyang Guo, Hong Tian, Yuan He, Yang Li, Xuelian Jiang, Haixue Zheng*, Shuqi Xiao*. Induction of HOXA3 by PRRSV inhibits IFN-I response through negative regulation of HO-1 transcription. Journal of Virology , 96（3）：e01863-21 (2022).
[3] Zhiwei Li, Zhiqian Ma, Linfang Dong, Ting Yang, Yang Li, Dian Jiao, Weiguo Han, Haixue Zheng, Shuqi Xiao*. Molecular mechanism of porcine epidemic diarrhea virus cell tropism. mBio , 13(2):e0373921 (2022).
[4] Angke Zhang, Lijuan Zhao, Na Li, Hong Duan, Hongliang Liu, Baicheng Huang, Fengxing Pu, Gaopeng Hou, Gaiping Zhang, En-Min Zhou*, Shuqi Xiao*. Carbon Monoxide Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication by the Cyclic GMP/Protein Kinase G and NF-κB Signaling Pathway. Journal of Virology , 91:1 pii: e01866-16 (2017).
[5] Shuqi Xiao, Xue Wang, Huaibao Ni, Na Li, Angke Zhang, Hongliang Liu, Fengxing Pu, Lele Xu, Jiming Gao, Qin Zhao, Yang Mu, Chengbao Wang, Yani Sun, Taofeng Du, Xingang Xu, Gaiping Zhang, Julian A. Hiscox, Ian G. Goodfellow, En-Min Zhou*. MiR-24-3p Promotes Porcine Reproductive and Respiratory Syndrome Virus Replication through Suppression of Heme Oxygenase-1 Expression. Journal of Virology , 89(8):4494-4503 (2015).
[6] Angke Zhang, Hong Duan, Na Li, Lijuan Zhao, Fengxing Pu, Chunyan Wu, Yuchen Nan, Taofeng Du, Yang Mu, Qin Zhao, Yani Sun, Gaiping Zhang, Julian A. Hiscox, En-Min Zhou*, Shuqi Xiao*. Heme oxygenase-1 metabolite biliverdin, not iron, inhibits porcine reproductive and respiratory syndrome virus replication. Free Radical Biology and Medicine , 102:149-161 (2017).
[7] Zhiqian Ma, Zhiwei Li, Linfang Dong, Ting Yang, Shuqi Xiao*. Reverse Genetic Systems: Rational Design of Coronavirus Live Attenuated Vaccines. Advances in Virus Research , 107:383-416 (2020).
[8] Lele Xu，Zhiqian Ma，Yang Li，Zhaoxia Pang，Shuqi Xiao*. Antibody dependent enhancement: Unavoidable problems in vaccine development. Advances in Immunology , 151:99-133 (2021).
[9] Zhiqian Ma, Tianyu Wang, Zhiwei Li, Xuyang Guo, Yangsheng Tian, Yang Li, Shuqi Xiao*. A Novel Biotinylated Nanobody-based Blocking ELISA for the Rapid and Sensitive Clinical Detection of Porcine Epidemic Diarrhea Virus. Journal of Nanobiotechnology , 17(1):96 (2019).
[10] Hong Duan, Zhiqian Ma, Lele Xu, Angke Zhang, Zhiwei Li, Shuqi Xiao*. A novel intracellularly expressed NS5B-specific nanobody suppresses bovine viral diarrhea virus replication. Veterinary Microbiology , 240: 108449 (2020).
6. Projects and Funding
[1] The molecular mechanism of interaction between porcine reproductive and respiratory syndrome virus and its secondary Aerococcus viridans . General Project, No. 32172846, National Natural Science Foundation of China (NSFC), 580,000 RMB Yuan, 2022 - 2025, grant holder.
[2] Infectious Diseases in Domestic Animals, No. 2021JC-18, Science Foundation for Distinguished Young Scholars of Shaanxi Province. 300,000 RMB Yuan, 2021 - 2023, grant holder.
[3] Novel Vaccine R&D of PRRSV, No. 2022KWZ-05, Major International Joint Research Project from Key R&D Project in Shaanxi Province, 400,000 RMB Yuan, 2022 – 2024, grant holder.